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Laziness
Keratinization, absence of granular layer, and depositation of antibodies
and complement components in the stratum corneum. Most notable is the
hyperproliferation of keratinocytes in the epidermis. These keratinocytes
exhibit an increased mitotic rate and have ten times the turnover rate of
normal keratinocytes. There is also an infiltration of CD4+ T lymphocytes,
monocytes and neutrophils into the epidermis. Recently there has been much
debate over whether psoriasis is mediated by an autoimmune process.
The disease affects roughly two percent of the population in the
United States. It has the greatest prevalence among Scand ....
Word count: 1951 - Page count: 8
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